Radiation Therapy and Nivolumab with Relatlimab-rmbw Achieved a Complete Response in Metastatic Cutaneous Melanoma to the Orbit

We present a patient with left orbital metastasis of cutaneous melanoma, treated with 30 Gy in 10 fraction radiation therapy followed by a combination of programmed death-1 inhibitor, nivolumab, and lymphocyte-activation gene inhibitor, relatlimab. The patient achieved a complete response to treatment, with no evidence of recurrence of the orbital mass, 17 months after treatment initiation.

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Publication Details

Journal
Ophthalmic Plastic and Reconstructive Surgery
Published
2026-01-12
DOI
https://doi.org/10.1097/iop.0000000000003162
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Radiation Therapy and Nivolumab with Relatlimab-rmbw Achieved a Complete Response in Metastatic Cutaneous Melanoma to the Orbit

Devarati Mitra, Kim O. Learned, Oded Sagiv, Amina L. Chaudhry et al.
Ophthalmic Plastic and Reconstructive Surgery
Ocular Oncology and Treatments
article

Radiation Therapy and Nivolumab with Relatlimab-rmbw Achieved a Complete Response in Metastatic Cutaneous Melanoma to the Orbit

Devarati Mitra, Kim O. Learned, Oded Sagiv, Amina L. Chaudhry, Brandon T. Sellers
article en

Abstract

We present a patient with left orbital metastasis of cutaneous melanoma, treated with 30 Gy in 10 fraction radiation therapy followed by a combination of programmed death-1 inhibitor, nivolumab, and lymphocyte-activation gene inhibitor, relatlimab. The patient achieved a complete response to treatment, with no evidence of recurrence of the orbital mass, 17 months after treatment initiation.

Ophthalmic Plastic and Reconstructive Surgery
The University of Texas MD Anderson Cancer Center (US), San Antonio Uniformed Services Health Education Consortium (US)
Good health and well-being
Openalex Percentile: Top 89%
Ocular Oncology and Treatments
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