Cytomorphological Features of Lymphoepithelial Carcinoma of the Lung: A Comparative Analysis of Aspiration and Exfoliative Cytology

Distinctive morphological features of lymphoepithelial carcinoma of lung are reproducible on cytologic specimens. Qualitative nuclear features (macronucleoli, marked nuclear membrane irregularity, and naked tumor nuclei) are the most consistently observed. Compared to exfoliative cytology, aspirated specimens show higher yield for diagnostic cytomorphologic features of lymphoepithelial carcinoma.

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Publication Details

Journal
Acta Cytologica
Published
2026-01-13
DOI
https://doi.org/10.1159/000550410
Primary Topic
Viral-associated cancers and disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Cytomorphological Features of Lymphoepithelial Carcinoma of the Lung: A Comparative Analysis of Aspiration and Exfoliative Cytology

Ka Pang Chan, Joanna K. M. Ng, Joshua Li, Shelly Y. Ni
Acta Cytologica
Viral-associated cancers and disorders
article

Cytomorphological Features of Lymphoepithelial Carcinoma of the Lung: A Comparative Analysis of Aspiration and Exfoliative Cytology

Ka Pang Chan, Joanna K. M. Ng, Joshua Li, Shelly Y. Ni
article en

Abstract

Distinctive morphological features of lymphoepithelial carcinoma of lung are reproducible on cytologic specimens. Qualitative nuclear features (macronucleoli, marked nuclear membrane irregularity, and naked tumor nuclei) are the most consistently observed. Compared to exfoliative cytology, aspirated specimens show higher yield for diagnostic cytomorphologic features of lymphoepithelial carcinoma.

Acta Cytologica
Chinese University of Hong Kong (HK), Queen Mary Hospital (CN), Prince of Wales Hospital (CN), University of Hong Kong (HK)
Chinese University of Hong Kong
Openalex Percentile: Top 88%
Viral-associated cancers and disorders
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