Differential effects of small extracellular vesicles from head and neck cancer patients on dendritic cell functions
Our results uncover mechanisms through which tumor-derived small extracellular vesicles modulate dendritic cell functions locally and systemically. These mechanisms may also affect dendritic cell-based vaccine efficacy.
Authors
- Sonja Ludwig (ORCID: https://orcid.org/0000-0001-9751-323X)
- B. Wollenberg
- T WHITESIDE
- Linda Hofmann (ORCID: https://orcid.org/0000-0002-0683-7659)
- Sai Gopal Krishna Yerneni
- Marie-Nicole Theodoraki
- Thomas K. Hoffmann
- Diana Huber
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- TUM Klinikum (DE)
- Mayo Clinic in Arizona (US)
- UPMC Hillman Cancer Center (US)
- University of Pittsburgh Medical Center (US)
- University Hospital Ulm (DE)
- University Medical Centre Mannheim (DE)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-14
- DOI
- https://doi.org/10.3389/fonc.2025.1680167
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Krebshilfe
- National Institutes of Health