Metabolic Demand, Renal Mass, and Glomerular Filtration Rate Changes in Men and Women: Lessons from Living Kidney Donors and Recipients

In health and disease, several factors influence GFR like renal mass, the presence or absence of renal reserve, metabolic demand, the capacity of the kidney to adapt to it and the effect of ageing and senescence. In all of them, gender differences play a relevant role, making differences between men and women a factor to consider in the analysis of GFR.