Left bundle branch vs biventricular pacing: mechanistic insights from a canine model
This study in a DHF animal model indicates that LBBP results in electrocardiographic, echocardiographic, and molecular recovery at least as good as that during BiVP. The superiority of LBBP is especially reflected in more pronounced normalization of cardiac cytoskeleton, calcium handling and energy metabolism.
Authors
- Guanzhi Chen
- Han Jin (ORCID: https://orcid.org/0000-0003-0148-9031)
- Shi Cheng (ORCID: https://orcid.org/0000-0002-6100-0907)
- M Y Zhang
- Yiran Hu (ORCID: https://orcid.org/0000-0003-3429-4003)
- L Chen
- Jianqiu Pei (ORCID: https://orcid.org/0000-0002-7935-0884)
- Pengkang He
- Hao Huang (ORCID: https://orcid.org/0000-0002-2697-5135)
- Xi Liu (ORCID: https://orcid.org/0000-0001-6924-5119)
- F P Prinzen
- Xiaxia Pan
- ligang ding
- Wei Hua
- Hui Li
- Sixian Weng
- Juwei Yang
- Kevin Vernooy
- Hongxia Niu
- Min Gu
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Fudan University (CN)
- University Medical Center (US)
- Maastricht University (NL)
- Beijing Anzhen Hospital (CN)
- Zhongshan Hospital (CN)
- Peking University First Hospital (CN)
- Shenzhen Institutes of Advanced Technology (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1093/eurheartj/ehaf1093
- Citations
- 1
- Primary Topic
- Cardiac pacing and defibrillation studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39