[18F]Fluorocholine PET/CT in a 15-year-old patient suggested HPT-JT syndrome with active cemento-ossifying fibroma

To our knowledge, this is the first reported case utilizing [18F]Fluorocholine PET/CT for the evaluation and management of HPT-JT syndrome with active presence of a maxillary cemento-ossifying fibroma. Given its superior sensitivity compared to conventional imaging, [18F]Fluorocholine PET/CT provided critical information for surgical planning and it might be a useful diagnostic tool for long-term disease monitoring. This case highlights the potential role of [18F]Fluorocholine PET/CT in detecting both parathyroid and jaw manifestations of HPT-JT syndrome, emphasizing the need for further research into its application in hereditary endocrine disorders.

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Journal
EJNMMI Research
Published
2026-01-14
DOI
https://doi.org/10.1186/s13550-025-01267-x
Primary Topic
Parathyroid Disorders and Treatments
Type
article
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article

[18F]Fluorocholine PET/CT in a 15-year-old patient suggested HPT-JT syndrome with active cemento-ossifying fibroma

Carmelo Lacognata, Maurizio Iacobone, D. Cecchin, Francesca Torresan et al.
EJNMMI Research
Parathyroid Disorders and Treatments
article

[18F]Fluorocholine PET/CT in a 15-year-old patient suggested HPT-JT syndrome with active cemento-ossifying fibroma

Carmelo Lacognata, Maurizio Iacobone, D. Cecchin, Francesca Torresan, Francesca Serani
article en

Abstract

To our knowledge, this is the first reported case utilizing [18F]Fluorocholine PET/CT for the evaluation and management of HPT-JT syndrome with active presence of a maxillary cemento-ossifying fibroma. Given its superior sensitivity compared to conventional imaging, [18F]Fluorocholine PET/CT provided critical information for surgical planning and it might be a useful diagnostic tool for long-term disease monitoring. This case highlights the potential role of [18F]Fluorocholine PET/CT in detecting both parathyroid and jaw manifestations of HPT-JT syndrome, emphasizing the need for further research into its application in hereditary endocrine disorders.

EJNMMI ResearchVol. 16(1)
University of Padua (IT)
Good health and well-being
Openalex Percentile: Top 91%
Parathyroid Disorders and Treatments
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[18F]Fluorocholine PET/CT in a 15-year-old patient suggested HPT-JT syndrome with active cemento-ossifying fibroma — Carmelo Lacognata, Maurizio Iacobone, et al. · EJNMMI Research (2026) | TGRS Research Map | TGRS