Association between heavy metals exposure and depression: findings of the NHANES from 2003 to 2020

Our findings link heavy metal mixtures to depression, identifying tungsten and antimony as risk contributors, versus inverse associations for mercury and thallium, with barium as a key interactive factor. Further studies are needed to validate these metal-specific impacts and uncover additional depression-linked metals.

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Publication Details

Journal
European journal of medical research
Published
2026-01-14
DOI
https://doi.org/10.1186/s40001-026-03850-x
Primary Topic
Heavy Metal Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
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article

Association between heavy metals exposure and depression: findings of the NHANES from 2003 to 2020

Yixu Chen, Houfeng Zhou, Tao Feng, Zhiyuan Ma et al.
European journal of medical research
Heavy Metal Exposure and Toxicity
article

Association between heavy metals exposure and depression: findings of the NHANES from 2003 to 2020

Yixu Chen, Houfeng Zhou, Tao Feng, Zhiyuan Ma, Yuting Fan
article en

Abstract

Our findings link heavy metal mixtures to depression, identifying tungsten and antimony as risk contributors, versus inverse associations for mercury and thallium, with barium as a key interactive factor. Further studies are needed to validate these metal-specific impacts and uncover additional depression-linked metals.

European journal of medical researchVol. 31(1)
Chengdu Fifth People's Hospital (CN), Second Affiliated Hospital of Chengdu University of Traditional Chinese (CN), Chengdu University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 90%
Heavy Metal Exposure and Toxicity
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