Ocular metastasis in breast cancer: management of clinical case reports and a literature review

In recent years, the incidence of breast cancer (BC) and its distant metastases, including ocular metastasis (OM), has continued to rise. However, reports on BC-OM remain scarce. OM is rare and often asymptomatic. It can be easily masked by metastases in other organs, increasing the risk of misdiagnosis, and thus warrants greater clinical attention. In this paper, we describe three cases of BC-OM, review its epidemiological and clinical features, and summarize diagnostic methods and treatment strategies. Our aim is to provide a reference for clinical practice, support standardized management, and ultimately improve patient survival and quality of life (QoL).

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-14
DOI
https://doi.org/10.3389/fonc.2025.1605881
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Ocular metastasis in breast cancer: management of clinical case reports and a literature review

Qian Cao, Yi Liu, Lingzhi Xu, Jizhuo Gao et al.
Frontiers in Oncology
Ocular Oncology and Treatments
article

Ocular metastasis in breast cancer: management of clinical case reports and a literature review

Qian Cao, Yi Liu, Lingzhi Xu, Jizhuo Gao, Man Li, Mengyao Huang
article en

Abstract

In recent years, the incidence of breast cancer (BC) and its distant metastases, including ocular metastasis (OM), has continued to rise. However, reports on BC-OM remain scarce. OM is rare and often asymptomatic. It can be easily masked by metastases in other organs, increasing the risk of misdiagnosis, and thus warrants greater clinical attention. In this paper, we describe three cases of BC-OM, review its epidemiological and clinical features, and summarize diagnostic methods and treatment strategies. Our aim is to provide a reference for clinical practice, support standardized management, and ultimately improve patient survival and quality of life (QoL).

Frontiers in OncologyVol. 15
Second Affiliated Hospital of Dalian Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Liaoning Province
Good health and well-being
Openalex Percentile: Top 89%
Ocular Oncology and Treatments
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Ocular metastasis in breast cancer: management of clinical case reports and a literature review — Qian Cao, Yi Liu, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS