Multimodal semantic knowledge of emotion concepts in frontotemporal dementia
The FST provides the first clear dissociation of sbvFTD from bvFTD, a distinction of critical clinical importance given their divergent pathological substrates and the absence of frontotemporal lobar degeneration specific biomarkers. The study also refines our understanding of semantic memory: contrasting sbvFTD with svPPA reveals complementary roles of the right and left ATLs in supporting emotion and tool knowledge, underscoring the graded, lateralized organization of the semantic system.
Authors
- Maya Henry
- Kyan Younes (ORCID: https://orcid.org/0000-0002-9912-1616)
- Rian Bogley
- Sheila T. Tran
- Eleanor R. Palser (ORCID: https://orcid.org/0000-0002-2760-4184)
- Hülya Ulugut (ORCID: https://orcid.org/0000-0002-5016-2505)
- Valentina Borghesani (ORCID: https://orcid.org/0000-0002-7909-8631)
- Michelle N. Shiota (ORCID: https://orcid.org/0000-0002-9762-915X)
- A R Cowen
- Maxime Montembeault (ORCID: https://orcid.org/0000-0002-9369-0498)
- Carly Millanski
- Janhavi Pillai
- Maria Luisa Gorno Tempini
- Maria Luisa Mandelli
- Katherine P. Rankin
- Zachary A. Miller
- Virginia E. Sturm
- Dacher Keltner
- Buddhika Ratnasiri
- Zoe Ezzes
Institutions
- University of Geneva (CH)
- Palo Alto University (US)
- Douglas College (CA)
- Douglas Mental Health University Institute (CA)
- HES-SO Genève (CH)
- University Memory and Aging Center (US)
- McGill University (CA)
- Arizona State University (US)
- The University of Texas at Austin (US)
- University of California, Berkeley (US)
- Stanford University (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-01-13
- DOI
- https://doi.org/10.64898/2026.01.12.26343893
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00