The association between smoking and clinical outcomes among spondylodesis patients: A systematic review and meta-analysis

In most instances, smokers appeared to experience worse outcomes following instrumented spinal procedures compared to non-smokers, and a hierarchical pattern was notable, with current smokers experiencing the worst outcomes, followed by former smokers compared to never-smokers. Future well-designed studies with proper adjustment for confounding are needed to further confirm these findings.

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Publication Details

Journal
PLoS ONE
Published
2026-01-13
DOI
https://doi.org/10.1371/journal.pone.0337799
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

The association between smoking and clinical outcomes among spondylodesis patients: A systematic review and meta-analysis

Anna B. Veldman, Chady Omara, Carmen Vleggeert‐Lankamp, Emily L. Wang et al.
PLoS ONE
Spine and Intervertebral Disc Pathology
article

The association between smoking and clinical outcomes among spondylodesis patients: A systematic review and meta-analysis

Anna B. Veldman, Chady Omara, Carmen Vleggeert‐Lankamp, Emily L. Wang, Sulaiman Sajed, Rania A. Mekary, Namita Kaler, John Kilgallon, Mahnoor Shafi
article en

Abstract

In most instances, smokers appeared to experience worse outcomes following instrumented spinal procedures compared to non-smokers, and a hierarchical pattern was notable, with current smokers experiencing the worst outcomes, followed by former smokers compared to never-smokers. Future well-designed studies with proper adjustment for confounding are needed to further confirm these findings.

PLoS ONEVol. 21(1)
Brigham and Women's Hospital (US), Johns Hopkins University (US), Massachusetts College of Pharmacy and Health Sciences (US), Johns Hopkins Medicine (US), Leiden University Medical Center (NL), Spaarne Ziekenhuis (NL)
Good health and well-being
Openalex Percentile: Top 90%
Spine and Intervertebral Disc Pathology
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The association between smoking and clinical outcomes among spondylodesis patients: A systematic review and meta-analysis — Anna B. Veldman, Chady Omara, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS