REMOVED: Pharmacokinetics, mass balance and metabolism of [14C] ADC189, a novel inhibitor of the polymerase acidic protein, in humans
The results of this study collectively indicate that [<sup>14</sup>C]ADC189 does not significantly bind to blood cells, and its primary excretion route is fecal excretion, while urinary excretion is a secondary route.
Authors
- Huan Zhou (ORCID: https://orcid.org/0000-0002-7316-8467)
- Tonghao Zhang (ORCID: https://orcid.org/0000-0001-6558-6557)
- Huiwen Wang (ORCID: https://orcid.org/0000-0002-8699-7555)
- Wang Hu
- Yuanyuan Xu
- Jiaxiang Ding
- Lu-Ning Sun
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Zhejiang University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- European Journal of Pharmaceutical Sciences
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1016/j.ejps.2026.107444
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00