Unveiling the prognostic role of FABP4 in early-onset colorectal cancer through big data analysis and preliminary clinical validation
FABP4 is a promising independent prognostic biomarker for EOCRC, associated with an immunosuppressive microenvironment and maybe a potential guidance for immunotherapy and chemotherapy selection. Further multi-center prospective studies are warranted to validate its clinical utility.
Authors
- Fan Yao (ORCID: https://orcid.org/0000-0002-4393-7296)
- Lipeng Zhao
- Yue Wu (ORCID: https://orcid.org/0000-0002-8071-7751)
- Xiaoliang Xing
- Yixin Li (ORCID: https://orcid.org/0009-0004-4478-297X)
- Shaohua He
- Peilin Qing
- Jie Li
- Weiwei Zou
- Shengjun Zhang
Institutions
- Huaihua University (CN)
- Changsha Medical University (CN)
- Hunan University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-13
- DOI
- https://doi.org/10.3389/fonc.2025.1689952
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hunan Provincial Science and Technology Department
- Hunan University