Liver kinome reveals PS1145 as therapeutic agent for mitigating systemic inflammation in alcohol-related liver disease
PS1145 blocks IKK phosphorylation and TLR dimerization, attenuating inflammation and improving liver pathology, highlighting its therapeutic potential in ALD.
Authors
- Jaswinder Singh Maras (ORCID: https://orcid.org/0000-0003-3938-362X)
- Babu Mathew (ORCID: https://orcid.org/0000-0003-3956-8659)
- N. Sharma
- Shvetank Sharma (ORCID: https://orcid.org/0000-0001-7139-2011)
- Anupama Kumari (ORCID: https://orcid.org/0000-0003-0579-5706)
- Tahseen Khan (ORCID: https://orcid.org/0000-0003-3254-1162)
- Rimsha Saif
- Mr. Yash Magar
- S. K. Sarin
- Vipul Sharma
- Deepanshu Deepanshu
- Vasundhra Bindal
- Abhishak Gupta
- Kavita Yadav
- Gaurav Tripathi
- Manisha Yadav
- Sushmita Pandey
- Dinesh Mani Tripathi
- Sanju Yadav
Institutions
- Institute of Liver and Biliary Sciences (IN)
- National Institute of Immunology (IN)
- Artemis Hospitals (IN)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1016/j.biopha.2026.118984
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00