Enhancing gougerotin production by screening endogenous promoters for the transporter gene gouM in Streptomyces albulus CK-15
This study demonstrates that using strong promoters to enhance the expression level of the transporter gene <i>gouM</i> can increase the yield of gougerotin, thereby providing a basis for subsequently using promoter engineering strategies to construct higher-yielding strains in the future.
Authors
- Ruixin Qiao
- Binghua Liu (ORCID: https://orcid.org/0000-0003-1901-996X)
- Qixing Zhou (ORCID: https://orcid.org/0000-0001-7483-7661)
- Beibei Ge
- Ning Zhang
- Kunping Zhou
Institutions
- Linyi University (CN)
- Institute of Plant Protection (CN)
- Chinese Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-01-13
- DOI
- https://doi.org/10.3389/fmicb.2025.1719042
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Linyi University
- National Key Research and Development Program of China