Thalassemia does not significantly affect embryo ploidy outcomes in women undergoing IVF with preimplantation genetic testing

Overall, no significant differences were observed after adjustment for age, BMI, and AMH; however, a mild decrease in euploid proportion was noted among thalassemia women aged 35-40 years. These findings suggest that thalassemia does not generally impair embryo chromosomal integrity but that careful counseling may be warranted in this specific age group.