Periostin deficiency leads to age-dependent craniofacial, dental, and skeletal morphological alterations in mice
Periostin deficiency induces alterations in craniofacial, dental, and skeletal morphologies during aging. Periostin is also required for normal trabecular remodeling. These findings underscore its essential role in skeletal integrity and provide insights into bone biology and aging-related tissue remodeling.
Authors
- Akiko Karakawa (ORCID: https://orcid.org/0000-0003-2099-7293)
- Yuki Azetsu
- M TAKAMI
- Natsuhiro Takahashi
- Nobuhiro Sakai (ORCID: https://orcid.org/0000-0002-0240-6480)
- Masahiro Chatani (ORCID: https://orcid.org/0000-0002-1002-1775)
- Yurie Sato
- Shugo Haga
- Akihiko Fujita
- Haruhisa Nakano
Institutions
- SHOWA Medical University (JP)
Publication Details
- Journal
- Journal of Oral Biosciences
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1016/j.job.2026.100734
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00