Personalizing bariatric metabolic surgery: Predictors of weight-loss success and risk of weight recurrence
Baseline metabolic health predicts weight-loss outcomes and recurrence risk. RYGB offered greater and more consistent mid-term weight loss, especially benefiting metabolically high-risk patients. Procedure choice must be individualized accounting for specific risk profile and potential complications. These results advocate for a precision-medicine approach in bariatric procedure selection.
Authors
- Ornella Verrastro
- Giulia Angelini (ORCID: https://orcid.org/0000-0001-6753-745X)
- Sara Russo (ORCID: https://orcid.org/0009-0005-7144-6506)
- Simona Panunzi
- Geltrude Mingrone
- Ebaa Al Ozairi
- Francois Pattou
- Amalia Gastaldelli
- Silvia Sabatini
- Marcello Pompa
- Andrea De Gaetano
- James R. Casella Mariolo
- Thomas Sparso
- Giovanni Casella
- Paul W. Franks
- Stefan Bornstein
- Caterina Guidone
- Dario Tuccinardi
- Carel W. Le Roux
Institutions
- University College Dublin (IE)
- Università Cattolica del Sacro Cuore (IT)
- Inserm (FR)
- Lund University (SE)
- Novo Nordisk (Denmark) (DK)
- Université de Lille (FR)
- Institut Pasteur de Lille (FR)
- Agostino Gemelli University Polyclinic (IT)
- Centre Hospitalier Universitaire de Lille (FR)
- Istituto di Fisiologia Clinica (IT)
- Institute for Biomedical Research and Innovation (IT)
- Campus Bio Medico University Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- National Research Council (IT)
- Ospedale Eugenio Morelli (IT)
- University Hospital Carl Gustav Carus (DE)
- Istituto di Analisi dei Sistemi ed Informatica Antonio Ruberti (IT)
- Dasman Diabetes Institute (KW)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Metabolism
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1016/j.metabol.2026.156495
- Primary Topic
- Bariatric Surgery and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00