Quantification and characterization of lung fibrosis in ARDS patients using picrosirius red staining
Lung fibrosis during ARDS is predominantly driven by the deposition of weakly stained, loose segments of collagen fibers, which is associated with impaired lung mechanics and poorer clinical outcomes. Future studies should define candidates for early anti-fibrotic therapies.
Authors
- Thomas Planté-Bordeneuve (ORCID: https://orcid.org/0000-0001-7154-9437)
- Marylène Lecocq
- V. Lacroix
- L. Gerard
- Charles Pilette (ORCID: https://orcid.org/0000-0001-6685-0356)
- Delphine Hoton (ORCID: https://orcid.org/0000-0002-7947-4561)
- Guillaume E. Courtoy (ORCID: https://orcid.org/0000-0001-9311-2105)
- C. Bouzin
- Joao Pinto Pereira
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- Vrije Universiteit Brussel (BE)
- CHU Dinant Godinne UCL Namur (BE)
- Universitair Ziekenhuis Brussel (BE)
- UCLouvain (BE)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fmed.2025.1726436
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00