A rapid method to reduce drug interferences for antibody measurements in pegunigalsidase alfa-treated patients with Fabry disease

We present a rapid alkaline-treatment based method to overcome drug interferences to measure at least free antibodies in patients treated with pegunigalsidase alfa.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-13
DOI
https://doi.org/10.3389/fimmu.2025.1724835
Primary Topic
Lysosomal Storage Disorders Research
Type
article
Field-Weighted Citation Impact
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article

A rapid method to reduce drug interferences for antibody measurements in pegunigalsidase alfa-treated patients with Fabry disease

Michael A. Rudnicki, Markus Cybulla, Malte Lenders, Eva Brand et al.
Frontiers in Immunology
Lysosomal Storage Disorders Research
article

A rapid method to reduce drug interferences for antibody measurements in pegunigalsidase alfa-treated patients with Fabry disease

Michael A. Rudnicki, Markus Cybulla, Malte Lenders, Eva Brand, Elisa Rudolph
article en

Abstract

We present a rapid alkaline-treatment based method to overcome drug interferences to measure at least free antibodies in patients treated with pegunigalsidase alfa.

Frontiers in ImmunologyVol. 16
Innsbruck Medical University (AT), University Hospital Münster (DE), Center for Rheumatology (US)
Good health and well-being
Openalex Percentile: Top 90%
Lysosomal Storage Disorders Research
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