Time to treatment failure and its predictors among children receiving first-line antiretroviral therapy in Tigray Region public general hospitals, North Ethiopia, 2024: Retrospective cohort study
The incidence of treatment failure among children receiving first-line ART was found to be high according to the UNAIDS virological suppression targets. Poor adherence, baseline CD4 count, and initial NVP-based regimen were predictors of time to treatment failure of ART. Hence, all children on ART should be closely monitored, mainly on these identified predictors.
Authors
- Yohannes Kinfe (ORCID: https://orcid.org/0000-0001-8529-9424)
- Berhe Beyene Gebrezgiabher (ORCID: https://orcid.org/0000-0002-2449-2113)
- Berhe Gebrehiwot Tewele
- Birhane Mekonen Negash
- Teklebrhan Kinfe Gebru
- Ainom Shimondi Shishay
- Efrem Shushay Berhe
- Misho Mlaw Kidane
- Tetemke Mekonen Tekea
Institutions
- Adigrat University (ET)
- Aksum University (ET)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1371/journal.pone.0339269
- Citations
- 1
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 32.78