Dydrogesterone versus levonorgestrel-releasing intrauterine system for abnormal uterine bleeding: a propensity score-matched analysis of long-term efficacy and recurrence

LNG-IUS offers superior short-term bleeding control and sustained long-term recurrence prevention, especially for structural AUB. Dydrogesterone effectively manages nonstructural etiologies but carries higher systemic adverse event rates. Treatment selection should be etiology-guided, balancing immediate symptom control versus recurrence prevention and individualized safety considerations.

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Publication Details

Journal
Gynecological Endocrinology
Published
2026-01-12
DOI
https://doi.org/10.1080/09513590.2025.2612154
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Dydrogesterone versus levonorgestrel-releasing intrauterine system for abnormal uterine bleeding: a propensity score-matched analysis of long-term efficacy and recurrence

Li Huang, Xiaoli Wei, Xiangzun Li
Gynecological Endocrinology
Uterine Myomas and Treatments
article

Dydrogesterone versus levonorgestrel-releasing intrauterine system for abnormal uterine bleeding: a propensity score-matched analysis of long-term efficacy and recurrence

Li Huang, Xiaoli Wei, Xiangzun Li
article en

Abstract

LNG-IUS offers superior short-term bleeding control and sustained long-term recurrence prevention, especially for structural AUB. Dydrogesterone effectively manages nonstructural etiologies but carries higher systemic adverse event rates. Treatment selection should be etiology-guided, balancing immediate symptom control versus recurrence prevention and individualized safety considerations.

Gynecological EndocrinologyVol. 42(1)
Beijing YouAn Hospital (CN)
Good health and well-being
Openalex Percentile: Top 91%
Uterine Myomas and Treatments
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