Alteration of brain metabolism in lacunar stroke based on 18F-FDG-PET/MRI analysis
Our study identified that LS is not merely localized brain damage; it also involves broader dysfunction across brain networks, thereby affecting advanced cognitive functions. The observed compensatory increase in global network efficiency in LS patients might serve to maintain cerebral glucose metabolism. These findings may indicate new target areas for future treatments.
Authors
- WU Jia-jia
- Mou-Xiong Zheng
- Xu-Yun Hua
- Xin Gao
- Yun-Ting Xiang
- Ling-Ling Li
- Jian-Guang Xu
- Jie Ma
- Jing Jin
- Rong-Rong Huang
- Jian-Hui He
Institutions
- Shanghai Medical Information Center (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Yueyang Hospital (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-01-13
- DOI
- https://doi.org/10.3389/fneur.2025.1710801
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00