Post Hoc Subgroup Analysis of Clinical Outcomes in Patients With High‐Risk Metastatic Hormone‐Naïve Prostate Cancer: Results From a 3‐Year Interim Analysis of the J‐ROCK Study

These findings suggest that novel ADT plus ARPI regimens for LATITUDE-criteria high-risk mHNPC may improve real-world outcomes compared with ADT monotherapy or CAB, particularly among patients with poor prognosis.

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Publication Details

Journal
The Prostate
Published
2026-01-12
DOI
https://doi.org/10.1002/pros.70118
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Post Hoc Subgroup Analysis of Clinical Outcomes in Patients With High‐Risk Metastatic Hormone‐Naïve Prostate Cancer: Results From a 3‐Year Interim Analysis of the J‐ROCK Study

Ryo Yano, S. Kawakami, K. Nakamura, H. Miyake et al.
The Prostate
Prostate Cancer Treatment and Research
article

Post Hoc Subgroup Analysis of Clinical Outcomes in Patients With High‐Risk Metastatic Hormone‐Naïve Prostate Cancer: Results From a 3‐Year Interim Analysis of the J‐ROCK Study

Ryo Yano, S. Kawakami, K. Nakamura, H. Miyake, Shigekatsu Maekawa, Sachie Okazaki, Rikiya Matsumoto, Hiroaki Tsuchiya, HIDEYASU MATSUYAMA, Yohei Tajima, Eri Adachi, H. Uemura, K. Fujimoto, Atsushi Mizokami
article en

Abstract

These findings suggest that novel ADT plus ARPI regimens for LATITUDE-criteria high-risk mHNPC may improve real-world outcomes compared with ADT monotherapy or CAB, particularly among patients with poor prognosis.

The ProstateVol. 86(5)
Iwate Medical University (JP), Yokohama City University Medical Center (JP), Kindai University Hospital (JP), Chiba University Hospital (JP), Kin-ikyo Chuo Hospital (JP), Kanazawa University Hospital (JP), Nara Medical University Hospital (JP), CMIC Group (Japan) (JP), Yamaguchi University Hospital (JP), Shizuoka General Hospital (JP), Shizuoka Medical Center (JP), Shonan Kamakura General Hospital (JP), Yamato Municipal Hospital (JP), Johnson & Johnson (Brazil) (BR), Kobe University (JP), Saitama Medical University (JP), Yokohama City University (JP)
Openalex Percentile: Top 90%
Prostate Cancer Treatment and Research
DOIOpen Access PDFOpenAlex
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Post Hoc Subgroup Analysis of Clinical Outcomes in Patients With High‐Risk Metastatic Hormone‐Naïve Prostate Cancer: Results From a 3‐Year Interim Analysis of the J‐ROCK Study — Ryo Yano, S. Kawakami, et al. · The Prostate (2026) | TGRS Research Map | TGRS