Electroacupuncture to point Baihui confers anxiolytic effects by promoting oxytocin release from PVN in Mice
Intermittent 1.5 mA EA at Baihui (GV20) mitigates anxiety-like behavior in mice via a PVN-derived, OXT-dependent pathway. This work clarifies the anatomical and molecular mechanisms underlying EA-mediated anxiety relief and provides a basis for further exploring functional connections between specific acupoints and brain regions.
Authors
- Dake Song
- Zaihua Zhao
- Hengxin Gong
- Ban Feng
- Min Wang
- Shuibing Liu
- Runsong Cao
- Kun Zhang
- Ke Cheng
- Xu-bo Li
- Ying-ying Zhang
- Yu-mei Wu
- Ruifan Zhao
Institutions
- Tang Du Hospital (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1186/s13020-025-01307-7
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China