Tramadol induced hypoxia signaling and paraptosis-like cell death in breast cancer cells via HIF-1α and ATF4 dependent pathways
Tramadol induced breast cancer cell death via paraptosis which highlights its therapeutic potential in targeting resistant cancer subtypes such as triple-negative breast cancer.
Authors
- Zih-Syuan Wu (ORCID: https://orcid.org/0000-0003-3342-4195)
- Shih‐Ming Huang (ORCID: https://orcid.org/0000-0001-9305-921X)
- Yi-Jen Huang (ORCID: https://orcid.org/0000-0001-9279-487X)
Institutions
- National Defense University (US)
- National Defense Medical College (JP)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Redox Report
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1080/13510002.2025.2588866
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00