Control of Blood Pressure Variability Across Behavioral States by Brainstem Adrenergic Neurons
RVLM<sup>C1</sup> neurons stabilize BP during changes in the behavioral state by integrating arousal-related central drive with baroreceptor feedback. Disruption of these neurons leads to increased short-term BP variability despite preserved mean BP, providing a potential neural mechanism underlying pathological BP instability.
Authors
- Daniel S. Stornetta (ORCID: https://orcid.org/0000-0002-5570-6276)
- Faye E. Berry
- Harsha Thakkalapally
- Ulrich M. Atongazi
- George M.P.R. Souza
- Leah F. Wisniewski
- Stephen B.G. Abbott
Institutions
- University of Mississippi Medical Center (US)
- University of Virginia (US)
Publication Details
- Journal
- Circulation Research
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1161/circresaha.125.326792
- Primary Topic
- Neuroscience of respiration and sleep
- Type
- article
- Field-Weighted Citation Impact
- 0.00