Role of NOX2 in the regulation of inflammatory and apoptotic pathways in congolese patients with type 2 diabetes in Brazzaville
NOX2 represents an integrative marker associated with metabolic, inflammatory and apoptotic imbalance in T2D. Its elevation in patients with family history and poor glycemic control suggests potential as a risk stratification biomarker, particularly relevant in sub-Saharan Africa where tools for predicting diabetic complications are limited.
Authors
- Ghislain Loubano-Voumbi
- Donatien Moukassa
- Charley Loumade Elenga-Bongo
- Juste Brunhel Kaya Gondo
- Evariste Bouénizabila
- Feddercen Kelly Helga Mayassi
- Jeancia Jordanie Mbemba Makele
Institutions
- Laboratoire National de Santé Publique du Congo (CG)
- Centre Hospitalier et Universitaire de Brazzaville (CG)
- Médecins du Monde (BE)
- Wildlife Conservation Society Congo (CG)
- Université Professionnelle d'Afrique (CG)
- Marien Ngouabi University (CG)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-01-13
- DOI
- https://doi.org/10.3389/fendo.2025.1748586
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00