Subinhibitory concentrations of tedizolid induce upregulation of virulence gene transcription in Staphylococcus aureus
Sub-MIC of tedizolid and linezolid could increase the mRNA levels of different types of virulence genes in S. aureus, with strain-dependent variations. These findings provide new insights into the potential role of oxazolidinones in bacterial virulence regulation.
Authors
- Q. Liu (ORCID: https://orcid.org/0009-0000-7803-441X)
- Chunyan He (ORCID: https://orcid.org/0000-0002-9909-8268)
- Wen Ying Lin
- Han Yang
- Wen Shu
- Wenjing Chen
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- The Journal of Infection in Developing Countries
- Published
- 2025-12-31
- DOI
- https://doi.org/10.3855/jidc.20386
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China