Ninjin'yoeito enhances saliva secretion in aged mice via nutritional, immune, anti-inflammatory, and anti-aging effects
Ninjin'yoeito enhances salivary secretion from the submandibular glands of aged mice by improving nutritional status, modulating immune function, suppressing chronic inflammation, and attenuating cellular aging. These results suggest that Ninjin'yoeito has potential applications as a complementary therapy for age-related dry mouth.
Authors
- Tomotaka Nodai
- Takashi Munemasa
- Chihiro Masaki (ORCID: https://orcid.org/0000-0001-5336-3356)
- Taro Mukaibo (ORCID: https://orcid.org/0000-0002-3650-9250)
- Yui Hirata Obikane
- Ryuji Hosokawa (ORCID: https://orcid.org/0000-0003-2668-3084)
- Akihiro Nakamura
- Tomoki Kurakata
- Yusuke Kondo
Institutions
- Kyushu Dental University (JP)
Publication Details
- Journal
- Journal of Oral Biosciences
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1016/j.job.2026.100739
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 0.00