Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in patients with colorectal cancer: a retrospective study

High NLR was identified as an independent prognostic factor for worse CSS in CRC patients. The association between NLR and PLR with CRC outcomes may vary across different age groups. These findings highlight the potential utility of NLR as a prognostic biomarker in CRC, particularly for CSS.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-13
DOI
https://doi.org/10.3389/fmed.2025.1630125
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
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article
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article

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in patients with colorectal cancer: a retrospective study

Mohammad M. Abufaraj, Tala A. Haddad, Huthifa Ghanayem, Layan Ismail et al.
Frontiers in Medicine
Inflammatory Biomarkers in Disease Prognosis
article

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in patients with colorectal cancer: a retrospective study

Mohammad M. Abufaraj, Tala A. Haddad, Huthifa Ghanayem, Layan Ismail, Shrouq Qudah, Daoud O Al Aruri, M. S. El Muhtaseb
article en

Abstract

High NLR was identified as an independent prognostic factor for worse CSS in CRC patients. The association between NLR and PLR with CRC outcomes may vary across different age groups. These findings highlight the potential utility of NLR as a prognostic biomarker in CRC, particularly for CSS.

Frontiers in MedicineVol. 12
University of Jordan (JO), Medical University of Vienna (AT)
Good health and well-being
Openalex Percentile: Top 89%
Inflammatory Biomarkers in Disease Prognosis
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