Six-year epidemiological dynamics of human respiratory syncytial virus infections in children in central China (2019-2024): pandemic suppression, 2023 resurgence, and immune debt effect

NPIs dramatically affected HRSV epidemiology. The intense post-suppression rebound strongly supports the "Immune debt" theory-accumulation of susceptible children driving resurgence. Establishing year-round, multi-pathogen surveillance systems is crucial for post-pandemic public health challenges.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2026-01-13
DOI
https://doi.org/10.3389/fcimb.2025.1691957
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

Six-year epidemiological dynamics of human respiratory syncytial virus infections in children in central China (2019-2024): pandemic suppression, 2023 resurgence, and immune debt effect

Yaodong Zhang, Zhiyi Xia, Adong Shen, Pengbo Guo et al.
Frontiers in Cellular and Infection Microbiology
Respiratory viral infections research
article

Six-year epidemiological dynamics of human respiratory syncytial virus infections in children in central China (2019-2024): pandemic suppression, 2023 resurgence, and immune debt effect

Yaodong Zhang, Zhiyi Xia, Adong Shen, Pengbo Guo, Xue Li, Igor Mokrousov
article en

Abstract

NPIs dramatically affected HRSV epidemiology. The intense post-suppression rebound strongly supports the "Immune debt" theory-accumulation of susceptible children driving resurgence. Establishing year-round, multi-pathogen surveillance systems is crucial for post-pandemic public health challenges.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Saint Petersburg Pasteur Institute (RU), Zhengzhou Children's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 89%
Respiratory viral infections research
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