Sequestration and Persistence of Methotrexate Bubbles within Silicone Oil Tamponade Following Pars Plana Vitrectomy
Early MTX bubble formation in SO-filled eyes likely reflects immiscibility of the aqueous drug solution and SO. Despite maintained reattachment, sequestration may alter drug distribution. Further research is needed to elucidate whether MTX is a risk factor for SO emulsification.
Authors
- Alejandro Itzam Marin
- Justin S. Yun (ORCID: https://orcid.org/0009-0009-1671-6875)
- Adrian C. Au
- Hamid Hosseini
Institutions
- University of California, Los Angeles (US)
- UCLA Medical Center (US)
- Doheny Eye Institute (US)
- Harbor–UCLA Medical Center (US)
Publication Details
- Journal
- Retinal Cases & Brief Reports
- Published
- 2026-01-12
- DOI
- https://doi.org/10.1097/icb.0000000000001866
- Primary Topic
- Retinal and Macular Surgery
- Type
- article
- Field-Weighted Citation Impact
- 0.00