Effects of GLP-1 receptor agonists on copeptin in euvolemic participants

Our analysis provides evidence that the GLP-1-RA dulaglutide inhibits the vasopressin system and proposes physiological mechanisms that may explain the role of GLP-1 in sodium and water balance.

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Publication Details

Journal
European Journal of Endocrinology
Published
2026-01-08
DOI
https://doi.org/10.1093/ejendo/lvag005
Primary Topic
Electrolyte and hormonal disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of GLP-1 receptor agonists on copeptin in euvolemic participants

Julie Celine Refardt, Bettina Winzeler, Clara Odilia Sailer, D. Vogt et al.
European Journal of Endocrinology
Electrolyte and hormonal disorders
article

Effects of GLP-1 receptor agonists on copeptin in euvolemic participants

Julie Celine Refardt, Bettina Winzeler, Clara Odilia Sailer, D. Vogt, Svenja Leibnitz, Mirjam Christ-Crain
article en

Abstract

Our analysis provides evidence that the GLP-1-RA dulaglutide inhibits the vasopressin system and proposes physiological mechanisms that may explain the role of GLP-1 in sodium and water balance.

European Journal of EndocrinologyVol. 194(2)
Brigham and Women's Hospital (US), Erasmus MC (NL), University Hospital of Basel (CH), Hospital Base (CL), University Hospital of Zurich (CH), Erasmus University Rotterdam (NL)
Openalex Percentile: Top 90%
Electrolyte and hormonal disorders
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