Empagliflozin improves renal injury of diabetic nephropathy complicated with hyperuricemia through AMPK by promoting autophagy and inhibiting apoptosis
Empagliflozin alleviates renal injury in diabetic nephropathy with hyperuricemia by activating AMPK, promoting autophagy, and inhibiting apoptosis, suggesting its potential therapeutic value in managing this complication.
Authors
- Yanmei Xu
- Zhiqin Zhang
- Qi Gao
- Chuanwen Xu
- Ting Wu
- Xiaoyan Wu
Institutions
- Wuhan University (CN)
- Wuhan Puai Hospital (CN)
- Wuhan Prevention and Treatment Center for Occupational Diseases (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- Saudi Pharmaceutical Journal
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1007/s44446-025-00054-y
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00