Comparative prognostic value of nine cardiorenal biomarkers for mortality among adults with prediabetes and diabetes

Among nine evaluated cardiorenal biomarkers, NT-proBNP, hs-cTnT, and cystatin C demonstrated the strongest and most consistent associations with all-cause and CCD mortality among adults with prediabetes and diabetes, as well as the highest incremental predictive value. These biomarkers may serve as key components in future risk stratification models for individuals with prediabetes or diabetes.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-01-13
DOI
https://doi.org/10.1111/dom.70470
Primary Topic
Diabetes Treatment and Management
Type
article
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article

Comparative prognostic value of nine cardiorenal biomarkers for mortality among adults with prediabetes and diabetes

Gongchang Guan, 惠汝太, Zhao Zhao, Xuetao Zhu et al.
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
article

Comparative prognostic value of nine cardiorenal biomarkers for mortality among adults with prediabetes and diabetes

Gongchang Guan, 惠汝太, Zhao Zhao, Xuetao Zhu, Qianwei Cui, Hui Pang, Chunyan Chai, Ling Zhu, Shasha Chen, Shenglin He
article en

Abstract

Among nine evaluated cardiorenal biomarkers, NT-proBNP, hs-cTnT, and cystatin C demonstrated the strongest and most consistent associations with all-cause and CCD mortality among adults with prediabetes and diabetes, as well as the highest incremental predictive value. These biomarkers may serve as key components in future risk stratification models for individuals with prediabetes or diabetes.

Diabetes Obesity and MetabolismVol. 28(4)
Shanxi Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Shaanxi Provincial People's Hospital (CN), Xi'an Honghui Hospital (CN), Tongren Hospital (CN), Wuhan No.1 Hospital (CN), First Affiliated Hospital of Xi'an Jiaotong University (CN), Second Affiliated Hospital of Xi'an Jiaotong University (CN), Shanxi Provincial People’s Hospital (CN), Nanjing Medical University (CN), Xi'an Jiaotong University (CN)
Reduced inequalities
Openalex Percentile: Top 90%
Diabetes Treatment and Management
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Comparative prognostic value of nine cardiorenal biomarkers for mortality among adults with prediabetes and diabetes — Gongchang Guan, 惠汝太, et al. · Diabetes Obesity and Metabolism (2026) | TGRS Research Map | TGRS