Evaluating the effect of renin-angiotension-aldosterone system inhibitors and beta blockers on the progression of bicuspid aortic valve aortopathy in adulthood: A retrospective cohort study

Our findings suggest that the chronic use of RAASi or BB was not associated with a blunted progression of BAV aortopathy in the adult population. These results highlight the need for larger, randomised studies to validate these observations and further explore potential preventative strategies in this population.

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Publication Details

Journal
International Journal of Cardiology Congenital Heart Disease
Published
2026-01-12
DOI
https://doi.org/10.1016/j.ijcchd.2026.100653
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Evaluating the effect of renin-angiotension-aldosterone system inhibitors and beta blockers on the progression of bicuspid aortic valve aortopathy in adulthood: A retrospective cohort study

Keren Skalsky, Miri Schamroth Pravda, Ilan Richter, Ofir Brem et al.
International Journal of Cardiology Congenital Heart Disease
Cardiac Valve Diseases and Treatments
article

Evaluating the effect of renin-angiotension-aldosterone system inhibitors and beta blockers on the progression of bicuspid aortic valve aortopathy in adulthood: A retrospective cohort study

Keren Skalsky, Miri Schamroth Pravda, Ilan Richter, Ofir Brem, Tamir Bental, Guy Witberg, Elchanan Samuel, Nili Schamroth Pravda, Ran Kornowski, Yaron Shapira
article en

Abstract

Our findings suggest that the chronic use of RAASi or BB was not associated with a blunted progression of BAV aortopathy in the adult population. These results highlight the need for larger, randomised studies to validate these observations and further explore potential preventative strategies in this population.

International Journal of Cardiology Congenital Heart DiseaseVol. 23
University of California, Los Angeles (US), Tel Aviv University (IL), Tel Aviv Sourasky Medical Center (IL), Rabin Medical Center (IL), Wolfson Medical Center (IL), Mattel Children's Hospital (US)
Good health and well-being
Openalex Percentile: Top 91%
Cardiac Valve Diseases and Treatments
DOIOpen Access PDFOpenAlex
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Evaluating the effect of renin-angiotension-aldosterone system inhibitors and beta blockers on the progression of bicuspid aortic valve aortopathy in adulthood: A retrospective cohort study — Keren Skalsky, Miri Schamroth Pravda, et al. · International Journal of Cardiology Congenital Heart Disease (2026) | TGRS Research Map | TGRS