Differential diagnosis of high-grade astrocytic gliomas based on CD44, SOX2, and CIRBP gene expression analysis

Original method based on marker gene expression ratios does not replace standard diagnostic protocols, but may be an additional tool for optimized diagnostic process. This approach will be valuable to minimize errors and personalize therapeutic strategies. The last one is critical for prognosis.

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Publication Details

Journal
Burdenko s Journal of Neurosurgery
Published
2025-12-30
DOI
https://doi.org/10.17116/neiro20258906214
Primary Topic
Glioma Diagnosis and Treatment
Type
article
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article

Differential diagnosis of high-grade astrocytic gliomas based on CD44, SOX2, and CIRBP gene expression analysis

Ya. A. Sliman, O.V. Kalennik, G.V. Pavlova, N.S. Samoilenkova et al.
Burdenko s Journal of Neurosurgery
Glioma Diagnosis and Treatment
article

Differential diagnosis of high-grade astrocytic gliomas based on CD44, SOX2, and CIRBP gene expression analysis

Ya. A. Sliman, O.V. Kalennik, G.V. Pavlova, N.S. Samoilenkova, E.A. Savchenko, S.F. Drozd, D.S. Lukash
article en

Abstract

Original method based on marker gene expression ratios does not replace standard diagnostic protocols, but may be an additional tool for optimized diagnostic process. This approach will be valuable to minimize errors and personalize therapeutic strategies. The last one is critical for prognosis.

Burdenko s Journal of NeurosurgeryVol. 89(6)
Burdenko Neurosurgery Institute (RU), Institute of Higher Nervous Activity and Neurophysiology (RU)
Good health and well-being
Openalex Percentile: Top 24%
Glioma Diagnosis and Treatment
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