Unveiling a hidden threat: whole genome sequencing exposes the cross-hospital spread of extensively drug-resistant Pseudomonas aeruginosa
WGS surveillance revealed an undetected intra-hospital transmission of XDR P. aeruginosa ST235 and its persistence in the environment for at least nine months. The findings underscore the importance of genomic surveillance in identifying AMR outbreaks, especially among patients returning from high-risk regions, and proactive infection control measures to prevent the spread of high-risk AMR clones in healthcare settings.
Authors
- Brendan T. Jones (ORCID: https://orcid.org/0000-0001-5106-2795)
- Nathanial K. Copeland (ORCID: https://orcid.org/0000-0003-1504-253X)
- François Lebreton (ORCID: https://orcid.org/0000-0002-7157-5026)
- Christopher Harens
- Angela Caldwell
- Han Ha Youn
- Michael J. Schweikert
- Edwin Kamau
- John Mark Velasco
- Patrick T. Kiernan
- Tatdanai Kitjawat
Institutions
- Naval Medical Center San Diego (US)
- Tripler Army Medical Center (US)
- University of the Philippines Manila (PH)
- Walter Reed Army Institute of Research (US)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-01-13
- DOI
- https://doi.org/10.3389/fmicb.2025.1741917
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 21.79
Funders
- Walter Reed Army Institute of Research