Integrating GFAP Testing With Clinical Scores for Prehospital Large Vessel Occlusion Detection in Patients With Acute Stroke (DETECT LVO)
Integrating LVO scores combined with GFAP measurements into the prehospital work-up of patients with acute stroke improves diagnostic accuracy for LVO prediction. In the future, this could enable direct transfers of patients with suspected LVO to endovascular centers with reduced misdiagnosis rates. Independent replication in diverse prehospital cohorts is warranted to confirm these findings.
Authors
- Stephan Barthelmes
- Andreas Heilgeist
- Love-Preet Kalra (ORCID: https://orcid.org/0000-0002-4079-3311)
- Kristaps Blūms
- Sebastian Luger
- H Baum
- Klodiana Meci
- Sabina Zylyftari
- Iris Voka
- Deepak Bos
- Stephan Meckel
Institutions
- Goethe University Frankfurt (DE)
- Institute for Transfusion Medicine (US)
- University Hospital Frankfurt (DE)
- Klinikum Ludwigsburg (DE)
Publication Details
- Journal
- Stroke
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1161/strokeaha.125.052349
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 31.52