Glutathione metabolism as a key regulator of oxidative hippocampal injury in sepsis-associated encephalopathy: an integrated proteomics and metabolomics study

Our findings demonstrate that glutathione metabolism serves as a pivotal hub in the pathogenesis of SAE. The identified glutathione-related pathways provide potential therapeutic targets for alleviating oxidative stress-induced hippocampal injury in SAE, offering new insights for the clinical management of SAE-related neurological damage.