Multiomics analysis reveals that chlorogenic acid alleviates heat stress-induced oxidative damage in prepubertal boar testes via the BLVRA-GPX3 pathway: in vivo and in vitro evidence
In conclusion, prepubertal HS impairs the spermatogenic capacity of boars. BLVRA may mediate the testicular protective effect of CGA, although in vivo validation of this pathway is needed. This study contributes to elucidating the mechanisms underlying the effects of HS on prepubertal boar testicular development using multiomics approaches, laying a foundation for the potential utilization of CGA in swine production.
Authors
- Jiajia Qi (ORCID: https://orcid.org/0009-0009-9347-9105)
- Dali Wang
- Jing Li
- Shaoxuan Zhang
- Boxing Sun
- Hao Sun
- Simin Liu
- Shuang Liang
Institutions
- Jilin University (CN)
- Shandong Academy of Agricultural Sciences (CN)
- Jilin Agricultural University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1186/s40104-025-01336-0
- Primary Topic
- Effects of Environmental Stressors on Livestock
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- People's Government of Jilin Province
- Jilin University
- State Key Laboratory of Supramolecular Structure and Materials