Optimal doses of mind-body exercise on neuroinflammation in individuals with neuropsychiatric disorders: A systematic review and dose-response meta-analysis

MBEs effectively reduce proinflammatory cytokines (IL-1β, IL-6) and enhance anti-inflammatory cytokine (IL-10) and neurotrophic factor (BDNF) in neuropsychiatric disorders. The optimal dosage ranges from 600 to 1000 MET-min/week. Given the impact of participant characteristics and MBE parameters, personalized prescriptions may enhance clinical outcomes and long-term neuroprotective effects.

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Publication Details

Journal
Brain Behavior & Immunity - Health
Published
2026-01-12
DOI
https://doi.org/10.1016/j.bbih.2026.101176
Primary Topic
Tryptophan and brain disorders
Type
article
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0.00
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article

Optimal doses of mind-body exercise on neuroinflammation in individuals with neuropsychiatric disorders: A systematic review and dose-response meta-analysis

Weiguang Ni, Guoyuan Huang, Qian Liu, Qingying Zheng et al.
Brain Behavior & Immunity - Health
Tryptophan and brain disorders
article

Optimal doses of mind-body exercise on neuroinflammation in individuals with neuropsychiatric disorders: A systematic review and dose-response meta-analysis

Weiguang Ni, Guoyuan Huang, Qian Liu, Qingying Zheng, Ying Zhao
article en

Abstract

MBEs effectively reduce proinflammatory cytokines (IL-1β, IL-6) and enhance anti-inflammatory cytokine (IL-10) and neurotrophic factor (BDNF) in neuropsychiatric disorders. The optimal dosage ranges from 600 to 1000 MET-min/week. Given the impact of participant characteristics and MBE parameters, personalized prescriptions may enhance clinical outcomes and long-term neuroprotective effects.

Brain Behavior & Immunity - HealthVol. 52
University of Southern Indiana (US), Shanghai Jiao Tong University (CN), Jilin University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), Changchun University (CN)
Good health and well-being
Openalex Percentile: Top 87%
Tryptophan and brain disorders
DOIOpen Access PDFOpenAlex
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Optimal doses of mind-body exercise on neuroinflammation in individuals with neuropsychiatric disorders: A systematic review and dose-response meta-analysis — Weiguang Ni, Guoyuan Huang, et al. · Brain Behavior & Immunity - Health (2026) | TGRS Research Map | TGRS