Thyroid dysfunction in elderly first-episode drug-naïve major depressive disorder patients with comorbid dyslipidemia: prevalence, clinical profile and associated factors

Abnormal thyroid function is highly prevalent in elderly FEDN MDD patients with ALM; clinical severity, glucose, and lipid levels contribute to this comorbidity. These findings suggest that elderly, first-episode MDD patients with dyslipidemia, particularly those with elevated BMI, high blood glucose, and severe depressive symptoms, should undergo routine screening for thyroid dysfunction to facilitate early intervention.