Incidence and characteristics of bipolar disorder in middle-aged adults: a prospective population-based study

Although our results support a later emergence of BD in middle-aged adults, they also suggest atypical first manifestations of this later disorder with a high proportion of mixed episodes and high comorbidity with drug use disorders. From a clinical point of view, our data highlight the necessity for a thorough screening for first manifestations of BD also in middle-aged people particularly in the presence of drug misuse, which may delay the earlier recognition of mood episodes.

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Publication Details

Journal
International Journal of Bipolar Disorders
Published
2026-01-12
DOI
https://doi.org/10.1186/s40345-026-00412-2
Primary Topic
Bipolar Disorder and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Incidence and characteristics of bipolar disorder in middle-aged adults: a prospective population-based study

Marie‐Pierre F. Strippoli, Sylfa Fassassi, Setareh Ranjbar, Julien Elowe et al.
International Journal of Bipolar Disorders
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article

Incidence and characteristics of bipolar disorder in middle-aged adults: a prospective population-based study

Marie‐Pierre F. Strippoli, Sylfa Fassassi, Setareh Ranjbar, Julien Elowe, Caroline L. Vandeleur, Martin Preisig, Alexandre Berney, Benjamin Lavigne, Armin von Gunten
article en

Abstract

Although our results support a later emergence of BD in middle-aged adults, they also suggest atypical first manifestations of this later disorder with a high proportion of mixed episodes and high comorbidity with drug use disorders. From a clinical point of view, our data highlight the necessity for a thorough screening for first manifestations of BD also in middle-aged people particularly in the presence of drug misuse, which may delay the earlier recognition of mood episodes.

International Journal of Bipolar DisordersVol. 14(1)
Hôpital de Cery (CH), University of Lausanne (CH)
Openalex Percentile: Top 90%
Bipolar Disorder and Treatment
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