Evaluation of the efficacy and safety of botulinum toxin type A injections for the prevention of aspiration complications in patients with neurogenic dysphagia and posterior sialorrhea of various etiologies
Incorporating salivary gland chemodenervation with incobotulinumtoxinA (100 U) into the diagnostic and treatment algorithm for neurogenic dysphagia and posterior sialorrhea is an effective and safe method for preventing aspiration complications. This technique significantly reduces sialorrhea intensity and the incidence of aspiration pneumonia, improves swallowing function, facilitates patient care, and enhances the rehabilitation prognosis for severe neurological patients, starting from the acute disease phase. Implementing this method into the routine practice of rehabilitation facilities is advisable to reduce mortality, disability, and the financial burden on the healthcare system.
Authors
- Svetlana Khatkova (ORCID: https://orcid.org/0000-0002-3071-4712)
- A V Knyazev
- A.P. Kilina
- O.A. Pogoreltseva
Institutions
- National Rehabilitation Center (KR)
- MerLion Pharma (Germany) (DE)
Publication Details
- Journal
- S S Korsakov Journal of Neurology and Psychiatry
- Published
- 2025-12-30
- DOI
- https://doi.org/10.17116/jnevro2025125121126
- Primary Topic
- Dysphagia Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00