Association of psychosis with cognitive impairment is mediated by amyloidopathy in cognitive impairment

These findings suggest that amyloid pathology may mediate the effect of baseline cognitive impairment on psychosis during disease in AD, highlighting a potential pathological link between cognitive decline and psychotic symptoms.

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Publication Details

Journal
Frontiers in Aging Neuroscience
Published
2026-01-12
DOI
https://doi.org/10.3389/fnagi.2025.1663120
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of psychosis with cognitive impairment is mediated by amyloidopathy in cognitive impairment

S C Park, Na Young Yeo, Young Ho Park, and the Alzheimer’s Disease Neuroimaging Initiative et al.
Frontiers in Aging Neuroscience
Schizophrenia research and treatment
article

Association of psychosis with cognitive impairment is mediated by amyloidopathy in cognitive impairment

S C Park, Na Young Yeo, Young Ho Park, and the Alzheimer’s Disease Neuroimaging Initiative, Jung-Min Pyun, Jae-Won Jang, Sang Yun Kim, Young Chul Youn, Sungjoo Han
article en

Abstract

These findings suggest that amyloid pathology may mediate the effect of baseline cognitive impairment on psychosis during disease in AD, highlighting a potential pathological link between cognitive decline and psychotic symptoms.

Frontiers in Aging NeuroscienceVol. 17
Kangwon National University (KR), Soonchunhyang University Hospital Seoul (KR), Seoul National University Bundang Hospital (KR), Kangwon National University Hospital (KR), Chung-Ang University Hospital (KR)
Alzheimer's Association, Demensförbundet
No poverty
Openalex Percentile: Top 90%
Schizophrenia research and treatment
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Association of psychosis with cognitive impairment is mediated by amyloidopathy in cognitive impairment — S C Park, Na Young Yeo, et al. · Frontiers in Aging Neuroscience (2026) | TGRS Research Map | TGRS