The impact of hypothyroidism on the risk of intrahepatic cholestasis of pregnancy: a large-scale study based on pregnant women with hypothyroidism in Shanghai, China

We found that CH was significantly associated with a greater risk of ICP. CH, especially TPOAb(+) CH, is associated with a greater risk of both early and severe ICP. Furthermore, the prevalence of ICP increases with increasing TSH and decreasing FT4.

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Publication Details

Journal
Journal of Global Health
Published
2026-01-12
DOI
https://doi.org/10.7189/jogh.16.04013
Primary Topic
Drug Transport and Resistance Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

The impact of hypothyroidism on the risk of intrahepatic cholestasis of pregnancy: a large-scale study based on pregnant women with hypothyroidism in Shanghai, China

Lin Yuan, Hao Ying, Yirong Bao, Xiaoxian Qu et al.
Journal of Global Health
Drug Transport and Resistance Mechanisms
article

The impact of hypothyroidism on the risk of intrahepatic cholestasis of pregnancy: a large-scale study based on pregnant women with hypothyroidism in Shanghai, China

Lin Yuan, Hao Ying, Yirong Bao, Xiaoxian Qu, Chuanlu Xu, Mu Lv, Zhijuan Cao
article en

Abstract

We found that CH was significantly associated with a greater risk of ICP. CH, especially TPOAb(+) CH, is associated with a greater risk of both early and severe ICP. Furthermore, the prevalence of ICP increases with increasing TSH and decreasing FT4.

Journal of Global HealthVol. 16
Shanghai Municipal Health Commission, National Natural Science Foundation of China, National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 89%
Drug Transport and Resistance Mechanisms
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