Damage to Polymer Coatings on Microguidewire Tips through Shaping and J-wiring for Optimizing Flow Diverter Deployment: A Scanning Electron Microscopy Study
Achieving adequate wall apposition is a crucial technical goal when deploying flow diverters to treat wide-neck cerebral aneurysms. The socalled J-wiring technique is a common method used to optimize flow diverter wall apposition. However, the frictional interaction between the shaping device and the microguidewire tip during the formation of the J-loop, as well as the interaction between the J-loop and the flow diverter during J-wiring, may potentially cause damage to the guidewire's coating. Three frequently used guidewires were tested in vitro in a silicone aneurysm model. Manual J-shaping of guidewire tips, along with the J-wiring technique (including J-shaping), caused damage to the surface coating of guidewires, as observed by scanning electron microscopy. Therefore, both mechanisms may contribute to the generation of polymer micro-fragments in patients treated with flow diversion.
Authors
- Esben Thormann (ORCID: https://orcid.org/0000-0002-2364-3493)
- Rasmus Holmboe Dahl (ORCID: https://orcid.org/0000-0002-2014-7400)
- René Wugt Larsen (ORCID: https://orcid.org/0000-0003-2983-6795)
- Goetz Benndorf
Institutions
- Baylor College of Medicine (US)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Neurointervention
- Published
- 2026-01-12
- DOI
- https://doi.org/10.5469/neuroint.2025.01130
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Faculty of Health and Medical Sciences, University of Western Australia
- Det Sundhedsvidenskabelige Fakultet, Københavns Universitet