An open-label observational study of the efficacy and tolerability of rapidly dissolving forms of aceclofenac and nimesulide for oral use in the treatment of patients with acute non-specific low back pain (ASTRA study)

The use of aceclofenac and nimesulide in a rapidly dissolving form for the preparation of a suspension for oral administration is an effective and safe option for the treatment of ANLP. Rapid onset of effect, ease of administration, and a favorable safety profile are important advantages of this NSAID formulation for patients. Aceclofenac in the form of a powder for the preparation of a suspension for oral administration is superior to rapidly dissolving nimesulide in the speed of pain relief and can be considered as a first-line treatment for patients with ANLP.