RNA transcripts in salivary extracellular vesicle cargo isolated from aged populations
Our results indicate that salEVs contain transcripts that are associated with pathways involved in neurodegeneration. The presence of these transcripts in salEVs suggest that saliva may be used to screen for biomarkers of neurodegenerative diseases.
Authors
- M. Pereira
- Sicheng Wen (ORCID: https://orcid.org/0000-0002-4428-3634)
- Hannah Alaimo
- Jill A. Kreiling (ORCID: https://orcid.org/0000-0003-4440-2039)
- John M. Sedivy (ORCID: https://orcid.org/0000-0001-9363-4253)
- E.M. Teixeira
- P. J. Quesenberry
- Yu Chang
- Jonathan D. Drake
- Jenna R Pracht
- Lori A. Daiello
- Zhijin Wu
- Maxfield M. G. Kelsey
Institutions
- Brown University (US)
- Rhode Island Hospital (US)
Publication Details
- Journal
- Frontiers in Aging
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fragi.2025.1707720
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 22.24
Funders
- National Institutes of Health
- National Institute of General Medical Sciences